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Senior Scientist, Mammalian Cell Line Engineering and Expression Optimization for ADCs, Bispecifics, with Focus on Non Natural Amino Acid Expression Systems

Location Gaithersburg, Maryland, United States Job ID R-242830 Date posted 05/01/2026
Typical Accountabilities: • Applies technical knowledge and expertise to achieve project targets in a timely fashion and to agreed quality standards • Develops and maintains a level of scientific knowledge and capability, perhaps extending to specialist expertise in a specific area of work • Represents specialism on relevant projects teams, ensuring the provision of appropriate and timely data to the team • Independently, designs and carries out analytical studies and experiments that require expert knowledge, and develops and validates appropriate test methodology and specifications to achieve project aims • Independently, assesses and reports data with a clear understanding of its reliability, interprets findings and draws authoritative conclusions and recommendations so that their significance can be appreciated • Provides training /guidance to junior scientists on technical and functional processes • Helps to develop new and innovative techniques and methodologies and draws up relevant investigations • Liaises with colleagues from other disciplines with the purpose of discussing project-related matters, sharing experiences and reporting progress • Contributes to the management of external collaborations, e.g. consultants and contract research organisations • Uses own knowledge and expertise to input into management decisions about channelling resources to reduce risk associated with inappropriate investment decisions • Develops own level of scientific competence by keeping abreast of relevant scientific developments, by collaborating with peer scientists or through contacts with external groups • Ensures that work is performed in accordance with appropriate Safety, Health & Environment (SHE), quality and compliance standards, e.g. Good Laboratory Practice (GLP) Typical People Management Responsibility (direct / indirect reports): • Approximate number of people managed in total (all levels) - 0 What is the global remit? (how many countries will the role operate in?): • Own country Education, Qualifications, Skills and Experience: • Essential: Bachelors degree or equivalent and relevant experience within the discipline; Experience in the pharmaceutical industry; Understanding of current principles and concepts in own area of work; Understanding of regulations and relevant compliance systems related to own area of work; General understanding of other Discovery / R&D disciplines and their role in achieving the objectives of research area; Understanding of patent and IP issues • Desirable: Specialist knowledge in a specific area related to Chemistry Key Relationship to reach solutions: • Internal (to AZ or team): Colleagues, senior staff and management; AZ project teams • External (to AZ): Contract research organisations; External Scientific community

Compensation Pay Range:

112,164.00 - 168,246.00 USD Annual

The annual base pay (or hourly rate of compensation) for this position is outlined above. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Date Posted

06-Jan-2026

Closing Date

19-Jan-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

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Glassdoor logo Rated four stars on Glassdoor

Great culture, great work assignments, supportive management. Rotation opportunity within the company. They value our people.